Lab Service Questions

Peptide testing is a comprehensive analytical process used to verify the identity, purity, potency, and quality of peptide compounds. It's crucial for researchers, pharmaceutical companies, and healthcare providers to ensure that peptides meet strict quality standards. Testing helps verify molecular structure, confirm concentration levels, and ensure the peptide is safe and effective for its intended use. We also offer contaminant screening including ICP-MS heavy metal testing and GC-MS residual solvent analysis.

We test a wide range of peptides including synthetic peptides, naturally occurring peptides, therapeutic peptides, cosmetic peptides, research peptides, and custom-designed peptides. Our laboratory is equipped to handle peptides of various sizes, from small dipeptides to large polypeptides and protein fragments. We can analyze both lyophilized (freeze-dried) and solution-based peptide samples. Common categories include growth hormone releasing peptides, antimicrobial peptides, signaling peptides, neuropeptides, and structural peptides.

Eligible routine testing takes 5-7 business days from the time we receive your sample. Complex analysis requiring multiple testing methods may take 7-10 business days. The timeline can vary depending on the specific tests requested, sample quantity, and current laboratory workload. We provide estimated completion dates when you submit your sample and send updates if any delays occur.

Yes, we provide peptide testing services to clients across all 50 states. We have streamlined shipping procedures and partnerships with major courier services to ensure safe and timely sample delivery from any location. Our laboratory is equipped to handle samples from academic institutions, pharmaceutical companies, research organizations, healthcare facilities, and individual researchers throughout the country. We also work with international clients and can arrange international shipping for qualified projects.

Our services include HPLC purity analysis, mass spectrometry identity confirmation, LAL endotoxin testing, ICP-MS heavy metals and GC-MS residual solvents. Stability studies and custom methods are scoped separately. Confirm the selected methods and sample requirements before shipping.

Our laboratory maintains accuracy levels of ±1-2% for purity determinations and ±0.5 Da for molecular weight measurements using high-resolution mass spectrometry. We follow strict quality control protocols, use calibrated reference standards, and participate in proficiency testing programs to ensure accuracy. All instruments are regularly calibrated and maintained according to manufacturer specifications and regulatory guidelines. Each analysis includes appropriate controls and is performed by certified laboratory technicians. We provide detailed uncertainty measurements with our reports and maintain full traceability of all measurements.

HPLC (High-Performance Liquid Chromatography) measures peptide purity by separating the target peptide from impurities and quantifying the percentage of pure peptide in the sample. It provides a purity percentage but doesn't confirm the exact molecular structure. Mass Spectrometry (MS) determines the precise molecular weight of your peptide and can identify structural variations, fragmentation patterns, and post-translational modifications. HPLC tells you how pure your peptide is, while MS confirms it's the correct peptide. We recommend both tests for comprehensive verification - HPLC for purity assessment and MS for identity confirmation.

Yes, we offer custom analytical services tailored to specific research needs. Our scientists can develop specialized testing protocols for unique peptides, novel applications, or specific regulatory requirements. Custom services include stability studies under various conditions, bioactivity assays, solubility testing, aggregation analysis, oxidation studies, and compatibility testing with different formulations. We work closely with clients to understand their objectives and design appropriate testing strategies. Custom protocols are validated before implementation and can be documented for regulatory submissions.

Minimum sample requirements vary by test type. For standard purity testing via HPLC, we need at least 1-2 mg of peptide. Mass spectrometry requires 0.5-1 mg. For comprehensive analysis including multiple tests, we recommend submitting 5-10 mg to ensure sufficient material for all analyses and potential retesting if needed. If you have limited sample quantity, contact us to discuss micro-analytical options. We make every effort to conserve sample material and can return unused portions upon request.

Samples should be sealed in clean, labeled vials or containers to prevent contamination. Lyophilized peptides should be kept dry and protected from moisture. Solution samples should be frozen if shipping will take more than 24 hours. Package samples with adequate cushioning to prevent breakage during transit. Use insulated shipping containers with ice packs or dry ice for temperature-sensitive peptides. Include a completed sample submission form with all relevant information. Ship via a reliable courier service with tracking. We can provide detailed packaging guidelines and arrange courier pickup for high-value samples.

Please include the peptide sequence or name, expected molecular weight, estimated purity (if known), concentration (for solutions), storage conditions, any known stability issues, intended use, specific tests requested, preferred timeline, and your contact information. If available, provide synthesis details, previous testing results, or certificate of analysis. This information helps us select appropriate testing methods, handle the sample properly, and interpret results accurately. Complete information also helps us identify potential issues and recommend additional analyses if needed.

Yes, we offer complimentary sample storage for up to 30 days after testing completion. Samples are stored under appropriate conditions (typically -20°C for peptides) to maintain stability. Extended storage beyond 30 days is available for a nominal fee. We can store samples under specific conditions if required (e.g., -80°C, desiccated, light-protected). Long-term storage options are available for ongoing projects or regulatory requirements. Stored samples can be retrieved for additional testing without requiring new sample submission.

Our comprehensive reports include detailed analytical data, chromatograms or spectra, purity percentages, molecular weight measurements, comparison to expected values, identification of impurities (when applicable), methodology descriptions, instrument parameters, analyst signatures, and certificate of analysis. Reports are professionally formatted and include all raw data necessary for publication or regulatory submission. We provide interpretation of results and can highlight any concerns or anomalies. Reports are delivered in PDF format with original chromatograms and spectra available as supplementary files.

Results are delivered electronically via secure email as password-protected PDF files. You'll receive an initial notification when testing is complete, followed by the full report with all supporting documentation. Hard copies can be provided upon request for an additional fee. For ongoing projects, we can set up secure portal access where you can view all historical test results and track current samples. All reports are archived in our secure system and can be retrieved at any time.

Absolutely. Our scientific team is available to discuss your results, explain analytical findings, and answer technical questions. We can schedule phone consultations or video conferences to review results in detail. We'll explain what each measurement means, how it relates to your peptide's quality, and what actions you might need to take based on the findings. For complex results or unexpected findings, we provide detailed interpretations and recommendations. Educational support is included with all testing services at no additional cost.

If results indicate quality issues, we provide detailed analysis of the problems identified, likely causes, and recommendations for resolution. We can perform additional testing to characterize the nature and extent of impurities or degradation. Our team offers consultation on potential corrective actions, whether that involves re-synthesis, purification, or storage modifications. We can test replacement samples at reduced rates to verify improvements. All findings are documented clearly to help you work with your peptide supplier or synthesis team to address quality concerns.

Our laboratory operates under strict quality management systems and follows Good Laboratory Practice (GLP) guidelines. We maintain certifications relevant to analytical testing and participate in proficiency testing programs to verify our analytical capabilities. Our quality assurance program includes regular instrument calibration, method validation, analyst training and certification, comprehensive documentation systems, and routine internal audits. We can provide documentation of our quality systems and certifications for regulatory submissions or institutional requirements.

We maintain strict data security protocols including secure electronic data management systems, access-controlled laboratory facilities, confidentiality agreements with all staff, encrypted data transmission, secure storage of reports and raw data, and controlled sample handling procedures. All data is backed up regularly and archived according to industry standards. We never share client information or sample data with third parties without explicit written permission. For sensitive projects, we can implement additional security measures and execute specific confidentiality agreements.

Yes, our test reports are suitable for regulatory submissions to the FDA, EMA, and other regulatory agencies. We follow current Good Manufacturing Practice (cGMP) principles and can provide documentation that meets regulatory requirements. Our reports include all necessary information such as methodology validation data, instrument qualifications, analyst credentials, chain of custody documentation, and quality control records. We can work with your regulatory team to ensure our testing and documentation meet specific submission requirements.

Yes, GLP-1 receptor agonist peptides are among our most frequently tested compounds. We provide purity testing, identity confirmation via mass spectrometry, and contaminant screening (heavy metals, residual solvents) for Semaglutide, Tirzepatide, Retatrutide, Liraglutide, and other GLP-1 peptides using validated methods specifically optimized for these sequences.

Yes, we can verify the concentration (potency) of compounded Semaglutide and Tirzepatide preparations using validated HPLC and UV spectroscopy methods. This is particularly important for compounded formulations where accurate dosing is critical. Our testing confirms whether the labeled concentration matches the actual peptide content.

GLP-1 peptides like Semaglutide are larger and more complex than many research peptides, requiring specialized chromatographic conditions and mass spectrometry parameters. We use optimized gradient methods and higher-resolution instruments for these sequences. Additionally, GLP-1 peptides with fatty acid modifications (like Semaglutide's C18 chain) require specific sample preparation techniques.

Submit your peptide to our lab for independent identity verification. Mass spectrometry confirms the molecular weight matches the expected peptide, while HPLC purity testing reveals the quality level. We compare results against known reference standards and can detect common counterfeiting issues like wrong peptides, severely degraded products, or vials containing little to no active peptide.

Ship lyophilized peptides in sealed, labeled vials with adequate cushioning via overnight courier (FedEx, UPS). For solution-based peptides, freeze samples and ship with ice packs or dry ice. Temperature-sensitive peptides should always be shipped with cold packs. Include a completed sample submission form with peptide name, expected sequence, and requested tests.

We can arrange prepaid FedEx overnight shipping labels for qualifying orders. Contact us when requesting your quote and we'll include shipping logistics in your project setup. For international shipments, we provide customs documentation guidance to ensure smooth delivery.

If we detect that a sample was compromised during transit (e.g., thawed solution samples, broken vials), we immediately notify you and document the condition. We offer complimentary retesting once a replacement sample is provided. We also provide packaging guidelines to minimize shipping risks.

Yes, we routinely receive packages containing multiple peptide samples. Ensure each vial is individually labeled with a unique identifier, and include a packing list that maps each vial to the requested tests. We process multi-sample submissions efficiently and can provide volume discounts.

Pricing varies based on the specific tests required, sample complexity, and turnaround time needed. Standard purity testing via HPLC typically ranges from $200-400 per sample. Mass spectrometry analysis ranges from $150-350. Comprehensive packages combining multiple tests offer better value. Volume discounts are available for multiple samples or ongoing projects. We provide detailed quotes upon request and can customize testing packages to fit your budget while meeting your analytical needs. Request a quote through our website for specific pricing.

Payment is due upon receipt of testing results for first-time clients. We accept major credit cards, wire transfers, purchase orders from established institutions, and ACH payments. Accounts are available for approved clients with Net 30 payment terms. For large projects, we can arrange milestone-based payment schedules. All quotes are valid for 30 days and include a detailed breakdown of costs. Sales tax applies where required by law. Payment information is processed securely and we never store credit card information on our systems.

If testing results appear anomalous or inconsistent with expectations, we offer complimentary retesting to verify findings. If an error on our part is identified, we provide full refund or reanalysis at no charge. Samples found to be compromised during shipping or storage will be retested once a replacement sample is provided. We stand behind the quality of our work and will work with you to ensure accurate, reliable results. Detailed terms and conditions are provided with every quote and can be reviewed before sample submission.

Roger Brown is the founder and CEO of ACS Laboratory, the analytical operation behind ACS Peptide Testing Labs. He has spent nearly two decades developing third-party HPLC, LC-MS, and ESI-MS methods for complex biomolecules including peptides, cannabinoids, and hemp derivatives. Roger founded the first cannabis testing laboratory in Florida in 2008 and has built ACS into an DEA-registered lab. Full bio at /about/roger-brown.

Roger leads an independent laboratory that is DEA-registered (#RA0571996) and Florida AHCA licensed. He has 17+ years of experience developing validated chromatography and mass spectrometry methods for low-level impurity analysis, quantitation, and reference-standard work — the same analytical disciplines required for peptide purity, identity, and contaminant testing. Under his leadership, ACS earned 21 Emerald Test™ Badges in a single year, the most of any U.S. laboratory.

Yes. Roger is the bylined author of the peptide editorial content published on acslabtest.com, including guides on reading a Certificate of Analysis, HPLC vs. mass spectrometry, GLP-1 peptide testing, compounding pharmacy quality programs, and peptide stability. Weekly news roundups in the Peptide News category are attributed to the ACS Editorial Team rather than Roger.

The fastest way to reach the team Roger built is to submit a quote request through this site — a member of the lab will follow up directly. For media, speaking, or partnership inquiries involving Roger specifically, mention that in your message and it will be routed to him. You can also connect with ACS Laboratory on LinkedIn.