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About Our Peptide Testing Laboratory

ACS Peptide Testing Labs is an independent analytical laboratory in Sun City Center, Florida. We test research peptides for purity, identity, contaminants, endotoxin, and moisture, and we do not sell the material we analyze.

ACS Laboratory, now part of Smithers

ACS Laboratory is now part of Smithers, a global testing and scientific services organization founded in 1925. The Smithers organization brings more than 100 years of scientific expertise and international laboratory resources.

Peptide testing is one of ACS Laboratory's analytical services, not its only area of work. Our peptide testing capabilities cover 103 peptides, with 5–7 business days for eligible routine testing.

ACS LaboratoryOfficial Smithers announcement

What we do, and what we do not do

We run analytical chemistry on peptide samples submitted by research laboratories, compounding pharmacies, and suppliers who need an outside opinion on what is actually in a vial. Work is performed at one facility rather than brokered out, which keeps sample handling and data review under one quality system.

We do not manufacture, compound, resell, or recommend peptide products, and we do not provide clinical or dosing advice. That separation is the point of a third-party laboratory: the result has to be usable whether it is favorable or not. If you are evaluating labs, our guide on how to choose a peptide testing lab lists the questions worth asking any provider, including us.

Instrumentation and analytical methods

Reverse-phase HPLC with UV/DAD detection

Chromatographic purity, related-substance profiling, and assay against a reference standard.

LC-MS (liquid chromatography-mass spectrometry)

Molecular weight confirmation and sequence identity, including detection of deletion and oxidation impurities.

ICP-MS

Heavy metal and elemental contaminant screening at trace concentrations.

Kinetic chromogenic LAL

Bacterial endotoxin quantification for injectable-route research material.

Karl Fischer titration

Residual moisture in lyophilized peptide powder, which drives stability and net peptide content.

Method selection depends on the question being asked. Our comparison of HPLC versus mass spectrometry for peptide analysis explains why purity and identity are separate tests, and peptide purity testing covers what a purity number does and does not tell you.

Quality practices

  • Methods developed and validated to validated analytical methodology, with system suitability run before each analytical batch.
  • Sample chain of custody recorded from receipt through disposal, with blind sample handling available on request.
  • Calibration against traceable reference standards, with certificate references recorded on the report.
  • Reports issued with chromatograms and method parameters so a third party can re-examine the underlying data.
  • No commercial relationship with peptide sellers, so testing outcomes carry no supply-side incentive.

Who reviews the science

Our laboratory team can answer method and sample questions before you order. Read about ACS Laboratory's leadership on the Roger Brown author page.

Credentials at a glance

A2LA accreditation mark
ISO/IEC 17025:2017
Accredited by A2LA
U.S. Drug Enforcement Administration seal
DEA Registered Laboratory
#RA0571996

Laboratory accreditation is limited to the current certificate scope. Peptide HPLC and LC-MS coverage has not been confirmed; do not assume a peptide test is accredited.

validated analytical methods

Analyses are run to validated analytical methodology with documented calibration and reference standards.

HPLC + LC-MS instrumentation

Purity by RP-HPLC, identity confirmation by LC-MS, plus contaminant, endotoxin, and moisture panels in-house.

5–7 business days for eligible routine testing

From sample receipt. Complex panels, custom methods and stability studies have separately confirmed timelines.

Independent, traceable COA

Every report includes chromatograms, method parameters, and sample chain-of-custody so results can be verified.

More detail on our instrumentation, analysts, and quality system is on the about our peptide testing laboratory page, or read how to verify a peptide COA.

Frequently asked questions about the lab

Who operates ACS Peptide Testing Labs?

ACS Peptide Testing Labs provides peptide analytical testing from ACS Laboratory, now part of Smithers. Samples are received, prepared and analyzed at the single Sun City Center, Florida facility.

Is the laboratory independent of peptide sellers?

Yes. We do not manufacture, resell, or distribute peptides. Testing revenue comes from analysis only, which is what makes a third-party certificate of analysis meaningful.

What standards do your methods follow?

Analyses follow validated analytical methodology, with method design informed by USP and ICH guidance for chromatographic purity, identity, and stability work.

How long does testing take?

5–7 business days for eligible routine testing from sample receipt. Complex panels, custom methods and stability studies have separately confirmed timelines.

Can results be verified independently?

Every report includes chromatograms, the analytical method parameters, and sample identifiers. A second laboratory can reproduce the analysis from that information, which is the practical test of whether a COA is trustworthy.

Send a sample or ask a method question

Tell us the compound, the format, and what you need to demonstrate. We will confirm the right panel, pricing, and shipping instructions before you ship anything.