GHK-Cu Cream Testing Services
GHK-Cu cream is a topical preparation of the copper tripeptide GHK-Cu in a cosmetic or compounded base. Testing confirms the labeled GHK-Cu concentration in the finished product, verifies copper-to-peptide ratio by ICP-MS, and screens for microbial contamination and oxidation byproducts that arise from formulation incompatibilities.
Research Applications
Common research areas for GHK-Cu Cream
- Compounded skincare QC
- Cosmetic formulation research
- Wound healing research preparations
Peptide Information
Molecular details and sample requirements
Sequence / Structure:
Gly-His-Lys + Cu(II) (topical base)
Molecular Weight
340.81 g/mol (active complex)
Formula
C14H24N6O4Cu (active)
Recommended Purity
Verified label claim
Sample Size
5-10 g finished cream
Our GHK-Cu Cream Testing Services
Comprehensive analytical testing to ensure GHK-Cu Cream quality and purity
Purity Testing
HPLC analysis to verify GHK-Cu Cream purity levels
Identity Verification
Mass spectrometry to confirm molecular identity
Third-Party Verification
Independent COA verification for GHK-Cu Cream
Certificate of Analysis
Official US laboratory documentation
Ready to test your peptides?
Send your peptide name, sample count, and the tests you need. We return a fixed-price quote, usually within one business day.
- validated analytical methods, independent of any supplier
- 9-11 business day standard turnaround
- Traceable COA with chromatograms and method parameters
GHK-Cu Cream Testing Methodology
Our analytical workflow for GHK-Cu Cream follows USP <1225> guidance for validated chromatographic methods. Each lot is processed by a credentialed analyst with documented chain of custody.
Step 1
Sample intake & chain of custody
Your GHK-Cu Cream sample (5-10 g finished cream) is logged at our Florida lab with a unique ID, photographed, and stored at -20 °C until analysis.
Step 2
Reverse-phase HPLC purity
GHK-Cu Cream is dissolved in mobile phase and run on a C18 column with a water/acetonitrile gradient containing 0.1% TFA. UV detection at 214 nm quantifies the main peak and any related impurities.
Step 3
LC-MS identity confirmation
An aliquot is analyzed by liquid chromatography-mass spectrometry. The observed monoisotopic mass is compared against the theoretical molecular weight (340.81 g/mol (active complex)) for GHK-Cu Cream to confirm identity.
Step 4
Impurity profiling & reporting
Related substances, truncations, and oxidation products are quantified. Findings are compiled into a signed Certificate of Analysis with chromatograms, mass spectra, and analyst interpretation.
GHK-Cu Cream Purity Notes
Recommended research-grade purity for GHK-Cu Cream is Verified label claim. Lot-to-lot variation is common with solid-phase synthesis, so independent verification matters.
Common impurities to watch
- Truncated sequences from incomplete coupling
- Deletion peptides missing one or more residues
- Oxidation of methionine, tryptophan, or cysteine
- Residual TFA, acetate, or solvent counter-ions
- Aggregates and dimers from improper storage
What our COA confirms
- Main peak purity by HPLC area %
- Observed vs theoretical mass (340.81 g/mol (active complex))
- Named impurities ≥ 0.1% area
- Net peptide content where applicable
- Method, column, and instrument metadata
GHK-Cu Cream Handling, Storage & Safety
Guidance below is for laboratory and research personnel only. GHK-Cu Cream is supplied for research use and is not intended for human or veterinary use.
Storage
Store lyophilized GHK-Cu Cream at -20 °C, protected from light and moisture. After reconstitution, aliquot and store at -80 °C; avoid repeated freeze-thaw cycles.
Reconstitution
Reconstitute in bacteriostatic or sterile water in a clean environment. Allow vials to reach room temperature before opening to prevent moisture condensation on the powder.
PPE & shipping
Handle with gloves, lab coat, and eye protection. Ship samples to ACS overnight on dry ice or cold packs in a rigid, leak-proof container with a packing slip referencing your quote.
This page is informational and does not constitute medical advice. Consult your institution's safety officer and SDS before working with GHK-Cu Cream.
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