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Melanotan II Testing Services

Melanotan II is a synthetic analog of alpha-melanocyte-stimulating hormone (α-MSH). It is a cyclic peptide that acts on melanocortin receptors and has been studied for various biological effects.

Research Applications

Common research areas for Melanotan II

  • Melanocortin receptor research
  • Pigmentation studies
  • Appetite and metabolism research
  • Sexual behavior studies

Peptide Information

Molecular details and sample requirements

Sequence / Structure:

Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH2

Molecular Weight

1024.18 g/mol

Formula

C50H69N15O9

Recommended Purity

≥98%

Sample Size

0.5-1 mg lyophilized

Our Melanotan II Testing Services

Comprehensive analytical testing to ensure Melanotan II quality and purity

Ready to test your peptides?

Send your peptide name, sample count, and the tests you need. We return a fixed-price quote, usually within one business day.

  • validated analytical methods, independent of any supplier
  • 9-11 business day standard turnaround
  • Traceable COA with chromatograms and method parameters

Melanotan II Testing Methodology

Our analytical workflow for Melanotan II follows USP <1225> guidance for validated chromatographic methods. Each lot is processed by a credentialed analyst with documented chain of custody.

  1. Step 1

    Sample intake & chain of custody

    Your Melanotan II sample (0.5-1 mg lyophilized) is logged at our Florida lab with a unique ID, photographed, and stored at -20 °C until analysis.

  2. Step 2

    Reverse-phase HPLC purity

    Melanotan II is dissolved in mobile phase and run on a C18 column with a water/acetonitrile gradient containing 0.1% TFA. UV detection at 214 nm quantifies the main peak and any related impurities.

  3. Step 3

    LC-MS identity confirmation

    An aliquot is analyzed by liquid chromatography-mass spectrometry. The observed monoisotopic mass is compared against the theoretical molecular weight (1024.18 g/mol) for Melanotan II to confirm identity.

  4. Step 4

    Impurity profiling & reporting

    Related substances, truncations, and oxidation products are quantified. Findings are compiled into a signed Certificate of Analysis with chromatograms, mass spectra, and analyst interpretation.

Melanotan II Purity Notes

Recommended research-grade purity for Melanotan II is ≥98%. Lot-to-lot variation is common with solid-phase synthesis, so independent verification matters.

Common impurities to watch

  • Truncated sequences from incomplete coupling
  • Deletion peptides missing one or more residues
  • Oxidation of methionine, tryptophan, or cysteine
  • Residual TFA, acetate, or solvent counter-ions
  • Aggregates and dimers from improper storage

What our COA confirms

  • Main peak purity by HPLC area %
  • Observed vs theoretical mass (1024.18 g/mol)
  • Named impurities ≥ 0.1% area
  • Net peptide content where applicable
  • Method, column, and instrument metadata

Melanotan II Handling, Storage & Safety

Guidance below is for laboratory and research personnel only. Melanotan II is supplied for research use and is not intended for human or veterinary use.

Storage

Store lyophilized Melanotan II at -20 °C, protected from light and moisture. After reconstitution, aliquot and store at -80 °C; avoid repeated freeze-thaw cycles.

Reconstitution

Reconstitute in bacteriostatic or sterile water in a clean environment. Allow vials to reach room temperature before opening to prevent moisture condensation on the powder.

PPE & shipping

Handle with gloves, lab coat, and eye protection. Ship samples to ACS overnight on dry ice or cold packs in a rigid, leak-proof container with a packing slip referencing your quote.

This page is informational and does not constitute medical advice. Consult your institution's safety officer and SDS before working with Melanotan II.

Get Your Melanotan II Tested Today

Contact us for a detailed quote and learn how our US laboratory COA can verify your Melanotan II quality

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