IGF-DES (1-3) Testing Services
IGF-DES (1-3), also called Des(1-3)IGF-1, is a truncated form of insulin-like growth factor 1 missing the first three N-terminal residues. It binds IGF binding proteins with much lower affinity, leaving more free peptide available in research models. We confirm the truncation by intact mass MS, quantify purity by RP-HPLC, and screen for full-length IGF-1 carryover.
Research Applications
Common research areas for IGF-DES (1-3)
- Muscle hypertrophy research
- IGF-binding protein studies
- Comparative IGF-1 analog research
Peptide Information
Molecular details and sample requirements
Sequence / Structure:
Truncated IGF-1 missing N-terminal Gly-Pro-Glu (residues 4-70)
Molecular Weight
~7,400 g/mol
Formula
Variant of IGF-1 (C331H512N94O101S7)
Recommended Purity
≥95%
Sample Size
0.5-1 mg lyophilized
Our IGF-DES (1-3) Testing Services
Comprehensive analytical testing to ensure IGF-DES (1-3) quality and purity
Purity Testing
HPLC analysis to verify IGF-DES (1-3) purity levels
Identity Verification
Mass spectrometry to confirm molecular identity
Third-Party Verification
Independent COA verification for IGF-DES (1-3)
Certificate of Analysis
Official US laboratory documentation
Ready to test your peptides?
Send your peptide name, sample count, and the tests you need. We return a fixed-price quote, usually within one business day.
- validated analytical methods, independent of any supplier
- 9-11 business day standard turnaround
- Traceable COA with chromatograms and method parameters
IGF-DES (1-3) Testing Methodology
Our analytical workflow for IGF-DES (1-3) follows USP <1225> guidance for validated chromatographic methods. Each lot is processed by a credentialed analyst with documented chain of custody.
Step 1
Sample intake & chain of custody
Your IGF-DES (1-3) sample (0.5-1 mg lyophilized) is logged at our Florida lab with a unique ID, photographed, and stored at -20 °C until analysis.
Step 2
Reverse-phase HPLC purity
IGF-DES (1-3) is dissolved in mobile phase and run on a C18 column with a water/acetonitrile gradient containing 0.1% TFA. UV detection at 214 nm quantifies the main peak and any related impurities.
Step 3
LC-MS identity confirmation
An aliquot is analyzed by liquid chromatography-mass spectrometry. The observed monoisotopic mass is compared against the theoretical molecular weight (~7,400 g/mol) for IGF-DES (1-3) to confirm identity.
Step 4
Impurity profiling & reporting
Related substances, truncations, and oxidation products are quantified. Findings are compiled into a signed Certificate of Analysis with chromatograms, mass spectra, and analyst interpretation.
IGF-DES (1-3) Purity Notes
Recommended research-grade purity for IGF-DES (1-3) is ≥95%. Lot-to-lot variation is common with solid-phase synthesis, so independent verification matters.
Common impurities to watch
- Truncated sequences from incomplete coupling
- Deletion peptides missing one or more residues
- Oxidation of methionine, tryptophan, or cysteine
- Residual TFA, acetate, or solvent counter-ions
- Aggregates and dimers from improper storage
What our COA confirms
- Main peak purity by HPLC area %
- Observed vs theoretical mass (~7,400 g/mol)
- Named impurities ≥ 0.1% area
- Net peptide content where applicable
- Method, column, and instrument metadata
IGF-DES (1-3) Handling, Storage & Safety
Guidance below is for laboratory and research personnel only. IGF-DES (1-3) is supplied for research use and is not intended for human or veterinary use.
Storage
Store lyophilized IGF-DES (1-3) at -20 °C, protected from light and moisture. After reconstitution, aliquot and store at -80 °C; avoid repeated freeze-thaw cycles.
Reconstitution
Reconstitute in bacteriostatic or sterile water in a clean environment. Allow vials to reach room temperature before opening to prevent moisture condensation on the powder.
PPE & shipping
Handle with gloves, lab coat, and eye protection. Ship samples to ACS overnight on dry ice or cold packs in a rigid, leak-proof container with a packing slip referencing your quote.
This page is informational and does not constitute medical advice. Consult your institution's safety officer and SDS before working with IGF-DES (1-3).
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