HPLC Purity Testing Cost Per Sample
Independent third-party HPLC purity testing at ACS starts at $150 per sample. Full contaminant panels for injectable-grade material run $500 to $1,200. Here is the complete breakdown so you can budget accurately and pick the right panel.
Get an Exact QuotePurity only
Purity + identity
Full injectable panel
Standard turnaround
What each panel includes
| Panel | Includes | Price range | Typical use |
|---|---|---|---|
| HPLC purity | HPLC + area % + chromatogram | $150–$300 | Baseline purity verification |
| Purity + identity | HPLC + LC-MS confirmation | $250–$450 | Confirms molecule + purity |
| Endotoxin (LAL) | Kinetic chromogenic USP <85> | $150–$300 | Any injectable |
| Heavy metals (ICP-MS) | USP <232>/<233> | $200–$400 | Pharmacy 503A/503B |
| Residual solvents | GC-headspace USP <467> | $200–$400 | Injectable-grade release |
| Full injectable panel | All of the above bundled | $500–$1,200 | Compounding pharmacy release |
Volume discounts
Per-sample pricing drops at defined thresholds:
- 1–4 samples: standard pricing
- 5–19 samples: approximately 10–15% reduction
- 20+ samples: contract pricing available
- Standing quarterly programs: bespoke pricing
Why prices vary between labs
Meaningful comparison is on methodology, not sticker price. A $75 purity test that skips method validation, uses a generic gradient, and returns a number without a chromatogram is not the same product as a $250 test that includes validated method conditions, integrated impurity profile, and raw data release. Look for documented method validation and USP compendial method compliance before comparing prices.
See also: in-house vs third-party testing, how to read a peptide COA, and the purity testing service overview.
Purity Testing Cost: FAQ
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