About this category
Khavinson bioregulators are very short peptides (di-, tri-, tetrapeptides) developed at the St. Petersburg Institute of Bioregulation and Gerontology. Their short length makes them inexpensive to synthesize but also easy to substitute or adulterate. We confirm exact sequence and quantify purity by HPLC + MS.
Featured peptides we test
Epitalon (Epithalon)
390.35 g/mol
Epitalon is a synthetic tetrapeptide based on the natural epithalamin peptide produced by the pineal gland. It is one of the most studied peptides in telomere biology, investigated for its ability to activate telomerase and potentially extend cellular lifespan.
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Pinealon
418.40 g/mol
Pinealon is a Khavinson tripeptide bioregulator targeting brain and pineal tissue. It is studied for cognitive support, neuroprotection, and circadian regulation in aging research.
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Vesugen
391.42 g/mol
Vesugen is a Khavinson tripeptide bioregulator targeting vascular tissue. It is studied for vascular endothelial function support in aging research.
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Vilon
275.30 g/mol
Vilon is a Khavinson dipeptide bioregulator with broad immunomodulatory effects. It is one of the most studied short peptide bioregulators in Russian gerontology research.
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Prostamax
472.49 g/mol
Prostamax is a Khavinson tetrapeptide bioregulator targeting prostate tissue. It is studied for prostate function support in aging research.
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Pancragen
561.59 g/mol
Pancragen is a Khavinson tetrapeptide bioregulator targeting pancreatic tissue. It is studied for pancreatic function support and glucose regulation in aging research.
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Thymagen / Thymogen
333.34 g/mol
Thymogen (and the related Thymagen) is a synthetic dipeptide bioregulator based on natural thymic peptides. It is studied for immune modulation, particularly for T-cell function support.
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Vesilute
391.42 g/mol
Vesilute is a Khavinson tripeptide bioregulator targeting bladder and urological tissue. It is studied for urinary tract function support in aging research.
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Sample submission
- Short peptides may need ion-pair HPLC for adequate retention.
- 0.5 mg sufficient.
- Specify whether free acid or amide form.
Common impurities
- Wrong sequence (substitution)
- Diketopiperazine cyclization
- Hydrolysis products
Recommended tests
- RP-HPLC (ion-pair)
- LC-MS Identity
Bioregulators Testing Methodology
Our analytical workflow for bioregulators peptides follows USP <1225> guidance for validated chromatographic methods. Every lot is processed by a credentialed analyst with documented chain of custody.
Step 1
Sample intake & cold storage
Each Bioregulators sample is logged with a chain-of-custody ID and stored at -20 °C upon arrival at our Florida lab.
Step 2
Reverse-phase HPLC purity
Samples are run on a C18 column using a water/acetonitrile gradient with 0.1% TFA, with UV detection at 214 nm to quantify main peak purity and named impurities.
Step 3
LC-MS / Orbitrap identity
Observed monoisotopic mass is compared against the theoretical mass for each bioregulators compound to confirm identity. Blends are deconvoluted to quantify each active component.
Step 4
Optional residual & endotoxin testing
Residual solvents (GC-MS), residual TFA / acetate counterions, and bacterial endotoxin (LAL) are run on request based on intended downstream use.
Step 5
Signed Certificate of Analysis
Findings are compiled into a signed COA with chromatograms, spectra, instrument metadata, and analyst interpretation, delivered within 9-11 business days.
Bioregulators Purity Notes
Recommended research-grade purity for bioregulators peptides is typically ≥ 98% by HPLC area. Synthesis-related impurities are common and only show up under proper analytical scrutiny.
Common impurities to watch
- Wrong sequence (substitution)
- Diketopiperazine cyclization
- Hydrolysis products
What our COA confirms
- Main peak purity by HPLC area %
- Observed vs theoretical monoisotopic mass
- Named impurities ≥ 0.1% area
- Net peptide content where applicable
- Method, column, and instrument metadata
Bioregulators Handling, Storage & Safety
Guidance below is for laboratory and research personnel only. Bioregulators peptides are supplied for research use and are not intended for human or veterinary use.
Storage
Store lyophilized material at -20 °C, protected from light and moisture. After reconstitution, aliquot and store at -80 °C; avoid repeated freeze-thaw cycles.
Reconstitution
Reconstitute in bacteriostatic or sterile water in a clean environment. Allow vials to reach room temperature before opening to prevent moisture condensation on the powder.
PPE & shipping
Handle with gloves, lab coat, and eye protection. Ship samples to ACS overnight on dry ice or cold packs in a rigid, leak-proof container with a packing slip referencing your quote.
This page is informational and does not constitute medical advice. Consult your institution's safety officer and SDS before working with these compounds.
Frequently asked questions
Related testing resources
- HPLC purity testing for bioregulators peptides
- Mass spectrometry identity confirmation (ESI-MS)
- Heavy metal and residual solvent screening
- LAL endotoxin testing for injectable peptides
- Peptide testing cost by assay
- How to ship peptides to our lab
- Independent third-party COA verification
- Peptide testing labs near me — all 50 states
- How to read a peptide Certificate of Analysis
- What peptide testing labs measure
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Sexual Health Peptide Testing
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Mitochondrial & Longevity Compound Testing
NAD+, MOTS-c, SS-31, Humanin, 5-Amino-1MQ, BAM15, and related longevity research compounds.
Growth & Muscle Peptide Testing
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Compounded Peptide Blend Testing
Component-level analysis of compounded peptide blends such as Tesamorelin/Ipamorelin and Retatrutide/Cagrilintide.